A postdoc position is available in Dr. Liang Han’s laboratory at Georgia Institute of Technology School of Biological Sciences (http://biosci.gatech.edu/people/liang-han). We use a combination of molecular genetic, immunohistochemical, fluorescence imaging and behavioral approaches to understand how the nervous system receives, transmits and interprets various stimuli to induce physiological and behavioral responses. We are particularly interested in the basic mechanisms underlying somatosensation, including pain, itch and mechanical sensation. Somatosensation is initiated by the activation of the primary sensory neurons in the peripheral nervous system. Our previous studies have identified the molecular identity of itch-sensing neurons in the peripheral. We are currently investigating how chronic itch associated with cutaneous or systemic disorders is initiated and transmitted and to search for new therapeutic targets for treating chronic itch conditions.
We are also interested in the physiological role of sensory neurons in the airway. The respiratory system is densely innervated by sensory neurons. We are investigating how sensory nerves in the airway contribute to the pathogenesis of chronic respiratory diseases such as asthma.
We are seeking a motivated and enthusiastic postdoc fellow to join our group. Candidates should have a Ph.D. focusing on biological science related field. Previous experience in neuroscience, and respiratory diseases is preferred.
Applicants should directly e-mail Dr. Liang Han at firstname.lastname@example.org a single PDF file that includes CV and names/contact information of three references.
- McNeil, B, Pundir, P, Meeker, S, Han, L, Undem, BJ, Kulka, M, Dong, X (2015). Identification of a mast cell specific receptor crucial for pseudo-allergic drug reactions. Nature. Mar 12;519(7542):237-41.
- Han, L*, Dong, X* (2014). Itch mechanisms and circuits. Annu Rev Biophys. 43:331-55., *corresponding authors.
- Han, L, Ma, C, Liu, Q, Weng, HJ, Cui, Y, Tang, Z, Kim, Y, Nie, H, Qu, L, Patel, KN, Li Z, McNeil B, He S, Guan Y, Xiao B, Lamotte RH, Dong X (2013). A subpopulation of nociceptors specifically linked to itch. Nat Neurosci 16, 174-182.
- Kim, Y, Chu, Y, Han, L, Li, M, Li, Z, LaVinka, PC, Caterina, MJ, Ren, K, Dubner, R, Wei, F, Dong, X (2014). Central terminal sensitization of TRPV1 by descending 5-HT facilitation is a key determinant of chronic pain, Neuron 81(4):873-87.
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