Room A110, Cherry Emerson Building, 310 Ferst Drive, Georgia Tech, Atlanta 30332-0230
PhD, University of Nottingham, U.K. (2001)
Sociomicrobiology, quorum sensing, biofilms, antimicrobial resistance, virulence
We are interested in how ecology and evolution shapes microbial cooperative behaviors and signaling systems (quorum sensing), and the implications of this for the evolution of virulence and antibiotic resistance during infection. Our emphasis is on chronic infections such as those found in cystic fibrosis lungs, diabetic ulcers and non-healing wounds. The main organisms that we focus on are the antibiotic resistant superbugs Pseudomonas aeruginosa and Staphylococcus aureus.
We are also determining whether ancient medieval recipes can be used to treat infectious disease (ancientbiotics). We build recipes in the lab which are translated from ancient texts, and test them against antibiotic resistant bacteria. We previously reconstructed a 10th century recipe from 'Bald's Leechbook' and demonstrated that it has anti-Staphylococcal activity.
For more information please visit our lab webpage.