The cycle of rising temperatures leads to increases in precipitation as well as droughts.  But what impact will these weather extremes, especially heavier precipitation, have on the earth’s most effective water cleansers – wetland sediments?  

That question is driving a new $1 million, three-year grant awarded to a Georgia Institute of Technology interdisciplinary research team of geochemistry, biology and applied mechanics experts.

The award is part of the Department of Energy’s $7.7 million funding of 11 studies to improve the understanding of Earth system predictability and the Department’s Energy Exascale Earth System Model, a state-of the-science climate model. The researchers intend to develop a new scalable model that can analyze and ultimately predict where and when sediment disruptions are most likely to occur. 

Wetlands – Where Water and Land Meet

Found at the boundary between land and water, wetlands function as natural sponges that trap, cleanse, and slowly release surface water – they also serve as a natural climate change buffer, since they act as carbon “sinks,” storing vast amounts of carbon and methane in the ground. Swamps, marshes, and bogs are all examples of wetlands. What isn’t known is if wetlands that become damaged or degraded from excess water will still absorb carbon at the same level.  

By better understanding how wetlands work, Georgia Tech hopes to shed light on how wetlands will function with more frequent and more intense rainstorms.   

“A lot of work has been done in polar regions where there has been melting because of global warming, which has been shown to release a lot of methane. That’s the main motivation behind the work we’re going to do,” said the project’s principal investigator, Martial Taillefert, a geochemist and professor in the School of Earth and Atmospheric Sciences. 

As water levels rise, below ground oxygen is consumed very quickly, he explained. Then microbial processes take over, leading to methane forming as well as carbon dioxide, that can escape to the atmosphere.

In this project Taillefert will characterize the physical and chemical processes taking place in a wetland, mainly using electrochemical sensors deployed at different locations in the wetland. Taillefert will be able to follow the chemical response to microbial processes and study how perturbations of the water cycle affect the release of greenhouse gases. This data will then be used to fine tune the models that will predict greenhouse gas emissions.

Micro to Macro Scale
Initial studies will involve samples on the scale of a few grains of soil, but the researchers hope to eventually run simulations on the scale of a riverbed or watershed (where surface water drains into a common stream channel or other body of water).

“The goal is twofold – first, to satisfy our scientific curiosity and understand how those microbial processes can actually change the level of oxygen and trigger greenhouse gas emissions, and second, to develop a model that can predict what processes will be in the next cycle to better prepare and perhaps reduce carbon emissions in some cases,” said project collaborator Chloé Arson, associate professor of Geosystems Engineering in the School of Civil and Environmental Engineering. 

While Taillefert focuses on the chemistry component and Arson on the mathematical modeling, collaborator Thomas DiChristina serves as the microbe expert.

“My lab looks at what kind of hidden microbial processes are going on that we can't detect with the sensors because the methane is getting recycled so fast in the ground,” said DiChristina, professor in the School of Biological Sciences. 

DiChristina will be looking at multiple gene expressions without having to grow the bacteria in a laboratory. 

“Genomics allows you to deduce expression of metabolic potential. For example, which gene is producing methane, and which gene is inhibiting methane production,” he said.

Since methane won’t release into the atmosphere unless a certain condition occurs, the model will enable researchers to predict under what conditions methane would pour out of the sediments versus being retained and recycled, DiChristina explained.

The calculations that predict how much methane and carbon dioxide go into the atmosphere depend on an accurate description of what's happening in the subsurface -- in the sediment and in groundwater, Taillefert added. 

“We cannot yet quantify that really well. We think using our approach will enable us to get more data and a better understanding of how the process works and translate that knowledge into the models,” he said.

Taillefert and DiChristina have been working on improving Georgia Tech’s models for predicting these processes for over three decades.  With this latest award, they hope to better understand and model the processes of oxidation and reduction that change the microstructure of sediments during cycles of flood.

New Research Thrust – AI and Machine Learning  

Arson is most interested in predicting the changes in the size, shape, and arrangement of the grains of soil to understand how the porous space between the grains is affected by bio-chemical reactions. 

“Understanding the evolution of the porous space will help predict transport properties within the sediments, and the expected emissions of greenhouse gases,” said Arson. 

An expert in applied mechanics, she will use AI to build a model that can single out dominant reactions within the soil microstructure and disregard those that have minimal impact. Such insight will help simplify the model and allow it to more quickly correlate certain criteria that leads to spikes in greenhouse gases. 

“If you have a predictive model that actually attempts to explain the processes, as well as predicting them, then you have a more versatile approach that can be transferred to many other sites or environments,” she said. “I also could envision using this model and the machine learning algorithm to map locations where you expect higher emissions, and identify sites as risky, moderately risky or safe.”

Georgia Tech is partnering with two Department of Energy (DOE) national laboratories: Savannah River National Laboratory (SRNL) in Aiken, SC, and Argonne National Laboratory in Chicago, IL.

“Georgia Tech has a unique capability here that we don't have, and that capability is this combination of using state-of-the-art genomics capabilities, along with state-of-the-art electrochemistry, two attributes that Georgia Tech is internationally known for,” said Daniel Kaplan, senior research fellow with SRNL, which will serve as the study site.

Kaplan noted that Georgia Tech’s research fits perfectly with the DOE’s goal to better understand how wetlands function, enabling scientists to better understand their role in controlling water quality.

“Wetlands do a great job of cleaning out all the impurities and getting rid of a lot of the contaminants to clean the water up as it moves through a watershed,” said Kaplan. 

Atomic-scale Analysis  

Argonne National Laboratory plans to take Georgia Tech’s sediment samples and examine them at the atomic scale of individual atoms and electrons using the Advanced Photon Source (APS), a football-field-sized synchrotron that produces x-rays 10 billion times clearer than what is produced at a doctor’s office.

“The fundamental reactions that are controlling the quality of the water happen at the microorganism or nano scale,” said Kenneth Kemner, senior physicist and group leader of the Molecular Environmental Science Group at the Argonne National Lab. “By bringing all the different ways of looking at wetlands together, we'll actually have a much deeper understanding of how they function.”

From one of several x-ray ports operated 24x7, the APS can capture images of single microorganisms about 100 times smaller than the diameter of the human hair. In fact, when the APS first came online, it successfully analyzed hair strands of Ludwig van Beethoven, with the analysis deducing that the great German composer suffered from lead poisoning.

Kemner acknowledged that Georgia Tech brings unique capabilities to the wetlands research effort. He explained that answering the hard questions such as those posed by climate change will require this transdisciplinary and integrated problem-solving approach. 

Additional unfunded collaborators for this study include Christa Pennacchio, PMO Lead with the Joint Genome Institute (JGI) at the Lawrence Berkeley National Laboratory (JGI), and Stephen Callister, scientist with the Environmental Molecular Sciences Laboratory (EMSL), a U.S. DOE national scientific user facility managed by Pacific Northwest National Laboratory.   

To help answer Scientific American's question, the authors seek the expertise of Joshua Weitz, Patton Distinguished Professor and Co-Director of the Interdisciplinary Ph.D. in Quantitative Biosciences in the School of Biological Sciences. Two tools built by Weitz's team are included: the Covid-19 Event Risk Assessment Planning Tool that estimates the probabilty of infection in groups of all sizes, given the rates of infection in an area; and a guide for estimating what proportion of each state's population has Covid-19 immunity, either through vaccination or natural infection. 

At the first ever CMDI-CDC Meeting on Infectious Disease Dynamics, held on June 10, 2021, researchers from the Centers for Disease Control and Prevention (CDC) and the Center for Microbial Dynamics and Infection at Georgia Tech (CMDI) came together virtually to discuss ecological and evolutionary perspectives on infectious disease dynamics.

“The mission of the CMDI is to transform the study and the sustainable control of microbial dynamics in contexts of human and environmental health,” notes Sam Brown, director of CMDI and professor in the School of Biological Sciences at Georgia Tech. “In keeping with this work, the CMDI-CDC Meeting on Infectious Disease Dynamics brought together these scientists as neighbors in Atlanta, and as organizations committed to the research of disease prevention and control.”

“In addition to showcasing the overlapping research interests of the CMDI and the CDC, the symposium also offered members of the Georgia Tech and CDC communities an open platform to ask questions of researchers in real time, as well as an opportunity to make new connections and encourage collaboration,” says Jennifer Farrell, a Ph.D. student studying microbiology at Georgia Tech who helped organize the meeting.

Farrell shares:

The online symposium drew 178 participants from across Georgia Tech and the CDC, setting the stage for continued communication and collaboration between the two institutions. The day kicked off with opening remarks from Brown and Juliana Cyril, director of the Office of Technology and Innovation, Office of Science, CDC.  Cyril and Brown each highlighted the unique relationships and collaborative potential between the two organizations.

Talks spanned pathogen systems, from the bacteria Pseudomonas aeruginosa and Streptococcus pneumoniae (Rich Stanton and Davina Campbell, CDC; Pengbo Cao, CMDI; Bernie Beall, CDC), to colonization dynamics of the fungal pathogen, Candida auris (Joe Sexton, CDC), to shield immunity in SARS-CoV-2 (Adriana Lucia-Sans and Andreea Magalie, CMDI).

Talks were further divided into research themes such as biofilm control (Pablo Bravo, CMDI; Rodney Donlan, CDC; Sheyda Azimi, CMDI) and microbiomes in infection (Commander Alison Laufer-Halpin, CDC; Jennifer Farrell, CMDI).

“In line with the commitment of the CMDI to promote trainee career development, the CMDI-CDC Meeting on Infectious Disease Dynamics was organized and run by Center graduate students and post-doctoral scientists, and CMDI talks were presented exclusively by Center trainees,” adds Farrell. “We look forward to continuing the conversation with our CDC colleagues in the future!”

Two charitable foundations have announced their support of research at the Georgia Institute of Technology that could change the basic understanding of DNA, potentially leading to new treatments for degenerative diseases.

The W.M. Keck Foundation and the G. Harold and Leila Y. Mathers Foundation have awarded grants of $1 million and $300,000, respectively, to boost the research of Francesca Storici, professor in the School of Biological Sciences and principal investigator for the projects. Both grants are directed toward decrypting the hidden message of ribonucleotide incorporation in human nuclear DNA.

The Mathers Foundation will cover work with the Storici lab only. The Keck Foundation is supporting a collaborative effort between Storici and Natasha Jonoska, professor of mathematics at the University of South Florida. Both Storici and Jonoska are founding members of the Southeast Center for Mathematics and Biology.

Full article by Jerry Grillo may be found here: https://research.gatech.edu/new-grants-could-transform-scientists-understanding-dna  

As the academic year comes to an end, the Student Government Association (SGA) is welcoming its new leadership. Samuel Ellis and Ajanta Choudhury were recently sworn in as the undergraduate SGA president and executive vice president, respectively. And Stephen Eick and PJ Jarquin will be taking over as graduate SGA president and executive vice president.

Eick, a Ph.D. student in computer science, comes from GSGA’s legislative branch, the Graduate Student Senate (GSS). Jarquin, a Ph.D. student in biomedical engineering, has spent his time in GSGA on the executive side, serving as vice president of campus services this year. He and Eick believe that, together, their experiences in different parts of student government will allow them to approach problems in a balanced way.

Ellis and Choudhury met in the Undergraduate House of Representatives (UHR) during the 2019-20 school year. After that, Ellis, an international affairs major, became vice president of external affairs, while Choudhury, a biology major, took a year away from SGA. They hope that being able to see SGA from different perspectives will help them provide solutions and address issues.

As their terms get underway, both teams are ready to jump into advocating for students. For the undergraduate executives, this largely focuses on academic policies, changing how students interact with the Office of Student Integrity, and helping with the shift to in-house dining in the fall. The graduate executives, meanwhile, are starting off by trying to help increase and consolidate mental health resources across campus, as well as advocate for new ways to support graduate researchers. Both groups agree that as Tech transitions toward a more familiar semester in the fall, they want to be involved in making sure that transparent, robust policies are in place to keep students safe.

Both sets of executives also share the desire to strengthen their particular side of SGA, which they feel will allow them to better advocate for students’ needs. For example, Eick has a goal of filling every seat in GSS by the end of the year.

“We hold ourselves back when we don’t have people engaged,” he said. As a member of GSS, Eick was the only representative for the College of Computing, which usually can have as many as nine representatives. He sees this as an excellent opportunity to increase both participation and diversity within GSGA.

“We want to make sure that we’re reaching different parts of campus whose voices aren’t usually heard,” Ellis said. For him, this means bringing new people into USGA by creating a recruitment chair position, as well as connecting people outside of the organization with Institute-wide committees where their input would be useful.

Each new executive also has a policy that they’re particularly excited to work on. For Ellis, it’s finding a way to address the problem of students experiencing homelessness; Choudhury wants to improve infrastructure for students with disabilities. Eick is passionate about building a participant recruiting board for research studies across campus to strengthen graduate student research, while Jarquin plans on advocating for more LGBTQ+-friendly health resources.

The new SGA leadership is ultimately humbled by the opportunity to serve their fellow students.

“To be in this role is to empower and uplift those in the same way that I felt empowered and uplifted by former executives in student government,” said Choudhury. “Being in this role isn’t just about improving the student experience, but really empowering the next generation of student leaders.”

“Coming from an immigrant father, being raised in the South, and being gay, it’s important for me to be in a role as visible as this,” Jarquin said. “It really is an honor to be in the position to fight for all graduate students.”

Applications are currently open to be an executive committee chair for undergraduate SGA; applications are rolling, but those interested should apply by Friday, May 7, to be considered. Learn more about each committee here. Elections for GSS and first-year representatives for UHR will happen in the fall; view the full list of seats in GSS and UHR.